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For additional information on these substances, contact the CFSAN Office of Food Additive Safety (HFS-200) at (240) 402-1200. Substances granted prior sanction for specific use prior to enactment of the Food Additives Amendment. Those pending administrative determination. Certain trade groups such as the Flavor Extract Manufacturers Association have established expert panels to evaluate and make determinations on the GRAS status of their products. The CFR does not contain a complete list of permissible flavorings. Synthetic flavoring substances in 21CFR 172.515. You may find such substances on an FDA web site, which contains received from companies sincE1998, and FDA's response. Obviously safe substances not cited in a regulation as Generally Recognized as Safe (GRAS). The Food Additive Status List omits certain categories of additives. Additives included are those specified in the regulations promulgated under the FD&C Act, under Sections 401 (Food

К списку документов This Food Additives Status List, formerly called Appendix A of the Investigations Operations Manual (IOM), organizes additives found in many parts of 21 CFR into one alphabetized list.

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